Hypothalamic-Pituitary Axis

Full name: HPA / HPG Axis

The hierarchical neuroendocrine signaling cascade connecting the hypothalamus, pituitary gland, and peripheral target glands. The growth hormone axis (GHRH → GH → IGF-1) and gonadal axis (GnRH → LH/FSH → testosterone/estrogen) are the two axes most frequently targeted by research peptides.